Larson Lab

Our research group is at the forefront of gene therapy for Parkinson's disease and other neurological disorders, with several clinical trials currently underway. We are also investigating the use of deep brain stimulation to treat tinnitus and continuing to advance the field of interventional MRI-guided surgery.

 

 

MRI-guided convection enhanced delivery of gene therapy for Parkinson's disease
Gene Therapy for Parkinson's Disease

We are extensively involved in several ongoing gene therapy trials for Parkinson’s disease, and continue to investigate the use of iMRI-guided convection enhanced delivery for gene therapy in other neurological disorders.

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Illustration depicting deep brain stimulation in the caudate nucleus for treatment of tinnitus
Tinnitus and Auditory Perception

We discovered that a specific area of the caudate (area LC) modulates auditory perception when stimulated, and recently completed the first-in-human phase I clinical trial to investigate the use of DBS in patients with tinnitus. 

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